Pharmacology: Zoledronic Acid Monohydrate belongs to the class of bisphosphonates and acts primarily on bone. It is an inhibitor of osteoclastic bone resorption.
The selective action of bisphosphonates on bone is based on their high affinity for mineralized bone, but the precise molecular mechanism leading to the inhibition of osteoclastic activity is still unclear. Zoledronic Acid Monohydrate inhibits bone resorption without adversely affecting the formation, mineralization or mechanical properties of bone.