Ronem Dosage & Drug Information

Concise Prescribing Info Bahasa Concise Prescribing Info

Concise Prescribing Info

Contents

Meropenem trihydrate

Indications/Uses

Treatment in adult & childn of infections caused by single or multiple bacteria sensitive to meropenem: Pneumonias & nosocomial pneumonias, UTI, intra-abdominal infections, gynaecological infections eg, endometritis, skin & skin structure infections, meningitis, septicaemia. Empiric treatment for presumed infections in adults w/ febrile neutropenia. Polymicrobial infections.

Dosage/Direction for Use

Pneumonia, UTI, gynecological infections eg, endometritis, skin & structure infections 500 mg IV 8 hrly. Nosocomial pneumonias, peritonitis, presumed infections in neutropenic patient, septicemia 1 g IV 8 hrly. Meningitis 2 g 8 hrly. Renal impairment CrCl 26-50 mL/min 1 unit dose 12 hrly; 10-25 mL/min ½ unit dose 12 hrly; <10 mL/min ½ unit dose 24 hrly.

Contraindications

Hypersensitivity.

Special Precautions

Hepatic disease. Pregnancy & lactation. Childn <3 yr.

Adverse Reactions

Inflammation, thrombophlebitis, pain at inj site, rash, pruritus, urticaria. Abdominal pain, nausea, vomiting, diarrhea, pseudomembranous colitis. Reversible thrombocythemia, eosinophilia, thrombocytopenia, leucopenia, neutropenia; increase in serum conc of bilirubin, transaminase, alkaline phosphatase & lactic acid dehydrogenase; headache, paresthesias; oral & vag candidiasis.

View ADR Monitoring Form

Drug Interactions

Probenecid, valproic acid, other nephrotoxics.

MIMS Class

Other Beta-Lactams

ATC Classification

J01DH02 - meropenem ; Belongs to the class of carbapenems. Used in the systemic treatment of infections.

Regulatory Classification

Presentation/Packing

Form

Ronem powd for inj 0.5 g

Packing/Price

0.5 g x 2 × 1's (Rp360,000/boks)

Form

Ronem powd for inj 1 g

Packing/Price

1's (Rp350,000/vial)

Ronem

meropenem

Manufacturer:

Fahrenheit