Ronazol

Ronazol

metronidazole

Manufacturer:

Gracia Pharmindo
Concise Prescribing Info
Contents
Metronidazole
Indications/Uses
Urethritis & vaginitis caused by Trichomonas vaginalis, intestinal & hepatic amoebiasis. Prophylaxis of post-op anaerob infections. Giardiasis due to Giardia lamblia.
Dosage/Direction for Use
Susp Intestinal & hepatic amoebiasis Adult 750 mg 3 times daily for 5-10 days. Childn 35-50 mg/kg/day in 3 divided doses for 10 days. Trichomoniasis Adult 2 g as a single dose for 1 day or 500 mg twice daily or 250 mg 3 times daily for 7 days. Childn 15 mg/kg/day in 3 divided doses for 7-10 days. Giardiasis Adult 250-500 mg 3 times daily for 5-7 days or 2 g once daily for 3 days. Childn 5 mg/kg 3 times daily for 5-7 days. Serious anaerob infections Adult 7.5 mg/kg 6 hrly. Max: 4 g daily for 7 days. Infusion Treatment of identified bacterial infections Adult 500 mg 8 hrly. Childn 7.5 mg/kg 8 hrly. Prophylaxis of post-op abdominal infections (especially colorectal), gynaecology Adult 500 mg pre-op followed by oral prep (500 mg) 8 hrly. Childn 7.5 mg/kg 8 hrly. All doses should be given at a rate of 5 mL/min & repeated 2 hrly.
Administration
Should be taken on an empty stomach: Take 1 hr before meals.
Contraindications
Known hypersensitivity to metronidazole or other nitroimidazole derivatives. 1st trimester of pregnancy.
Special Precautions
Perform blood test in prolonged use. CNS disorders, liver disease. Alcohol consumption may cause abdominal cramps, nausea, vomiting, headache & flushing. Lactation. Childn.
Adverse Reactions
Nausea, anorexia, epigastric pain; convulsive seizure, peripheral neuropathy; taste disturbances, furred tongue, vomiting, GI disturbances; urticaria, skin redness, angioedema & anaphylaxis, drowsiness, dizziness, headache, ataxia, darkened urine; reversible leucopenia.
Drug Interactions
Antibiotic, warfarin, coumarin anticoagulants, cimetidine, alcohol, disulfiram.
MIMS Class
Antiamoebics
ATC Classification
P01AB01 - metronidazole ; Belongs to the class of nitroimidazole derivatives antiprotozoals. Used in the treatment amoebiasis and other protozoal diseases.
J01XD01 - metronidazole ; Belongs to the class of imidazole derivative antibacterials. Used in the systemic treatment of infections.
Presentation/Packing
Form
Ronazol infusion 500 mg/100 mL
Packing/Price
(softbag) 100 mL x 1's
Form
Ronazol oral susp 125 mg/5 mL
Packing/Price
60 mL x 1's (Rp32,000/botol)
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