Lower resp tract infection, community-acquired pneumonia, acute exacerbation of COPD.
Dosage/Direction for Use
AdultCommunity-acquired pneumonia & acute exacerbation of COPD Initially 400 mg as a single dose on day 1, then 200 mg daily for 10 days.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity to sparfloxacin & other quinolones. Patients w/ a history of muscle/tendon disease due to fluoroquinolones; G6PD deficiency. Pregnancy & lactation. Infant, childn & adolescents.
Special Precautions
Avoid exposure to sunlight or UV radiation until 5 days after the end of treatment. May prolong the QT interval. Tendonitis or tendon impairment.
Adverse Reactions
GI disorders, insomnia, somnolence, convulsion, skin reaction, photosensitivity, rash or urticaria. Transient rise in liver transaminases.
Sucralfate, Fe sulfate, Al- or Mg-containing antacids may decrease sparfloxacin absorption. Increased conc w/ digoxin. Cisapride may result in increased absorption.
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