Pulmicort

Pulmicort

budesonide

Manufacturer:

AstraZeneca
Concise Prescribing Info
Contents
Budesonide
Indications/Uses
Bronchial asthma. Moderate to severe acute laryngotracheobronchitis (croup) in infants & childn, acute exacerbation of asthma, exacerbations of COPD.
Dosage/Direction for Use
Individualized dosage. Bronchial asthma Adult & childn ≥12 yr Initially 1-2 mg twice daily. Maintenance: 0.5-1 mg twice daily. Childn 3 mth-12 yr Initially 0.5-1 mg twice daily. Maintenance: 0.25-0.5 mg twice daily. Acute laryngotracheobronchitis (croup) Infant & childn 2 mg of nebulised as single administration. Acute exacerbations of asthma Adult 4-8 mg divided into 1-4 administrations. May be further increased in very severe cases. Max: 4 mg at one occasion. Can be continued until clinical improvement, max 10 days. Childn (6 mth-17 yr) 1.5-4 mg, up to 6 mg in childn ≥5 yr. Daily dose can be divided into 1-4 administrations. Max: 3 mg at one occasion. Can be continued until clinical improvement, max 10 days. Exacerbations of COPD 4-8 mg divided into 2-4 administrations, until clinical improvement, but max 10 days.
Contraindications
Special Precautions
Not indicated for rapid relief of bronchospasm. Not suitable as sole therapy for status asthmaticus or other acute asthma exacerbations. HPA axis suppression & adrenal insufficiency, bone density, growth; infections & TB; impaired liver function. Do not use w/ +ve pressure delivery systems. Pregnancy.
Adverse Reactions
Mild irritation in the throat, coughing, hoarseness; Candida infection in the oropharynx. Sore throat, tongue & mouth irritation, dry mouth.
Drug Interactions
Increased systemic exposure w/ CYP3A4 inhibitors eg, ketoconazole, itraconazole.
MIMS Class
Antiasthmatic & COPD Preparations
ATC Classification
R03BA02 - budesonide ; Belongs to the class of other inhalants used in the treatment of obstructive airway diseases, glucocorticoids.
Presentation/Packing
Form
Pulmicort respules 0.25 mg/mL
Packing/Price
2 mL x 20 × 1's (Rp566,211/boks)
Form
Pulmicort respules 0.5 mg/mL
Packing/Price
2 mL x 20 × 1's (Rp702,258/boks)
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