Patients w/ peptic ulcer, heart failure, HTN, blood clotting disorder, asthma, & SLE. Not to be taken concomitantly w/ aspirin or other medicines that contain paracetamol or ibuprofen, as well as anticoagulant drugs (anti-blood clotting) group warfarin. Experienced any unwanted effects while using Progesic or if after 5 days the pain has not been relieved. Kidney function impairment. Not recommended for pregnant & lactating women.