Do not inject intravascularly or intradermally. Reduced immunogenicity by immunosuppressive treatment or immunodeficiency. Guillain-Barre syndrome or brachial neuritis; thrombocytopenia or bleeding disorder. Vaccination must be preceded by medical history screening especially w/ regard to vaccination history & any occurrence of undesirable events & a clinical exam. Carefully consider giving further doses in: Fever ≥40°C not due to another identifiable cause, collapse or shock-like state (hypotonic-hyporesponsive episode), persistent, inconsolable crying lasting ≥3 hr w/in 48 hr vaccination, convulsions w/ or w/o fever occurring w/in 3 days of vaccination. Monitor temp & regularly give antipyretics for 48 hr following vaccination. Assess history of afebrile convulsion not related to a previous vaccine inj. Administer in 2 separate inj sites & on 2 different days the 2 vaccines, diphtheria-tetanus-pertussis-poliomyelitis vaccine & the
H. influenzae type b conjugate vaccine in the event of oedematous reactions occurring in the lower limbs after inj. Does not protect against invasive diseases caused by serotypes other than
H. influenza type b nor against meningitis from other origins. Potential risk of apnoea; monitor resp for 48-72 hr after primary immunisation to very premature infants (≤28 wk of gestation) & particularly for those w/ previous history of resp immaturity; do not w/hold or delay vaccination. Interference w/ lab urine test. Phenylketonuria. Intended for paed use only.
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