In combination w/ cisplatin for chemotherapy-naive patients w/ unresectable malignant pleural mesothelioma. 1st-line treatment w/ cisplatin in patients w/ locally advanced or metastatic NSCLC other than predominantly squamous cell histology. Monotherapy for the maintenance treatment of locally advanced or metastatic non-small cell lung cancer other than predominantly squamous cell histology in patients whose disease have not progressed immediately following platinum-based chemotherapy. As a single-agent for the treatment of patients w/ locally advanced or metastatic nonsquamous non-small cell lung cancer after prior chemotherapy (as 2nd line).