Adult 750 mg-1.5 g 8 hrly.
Uncomplicated UTI, skin & skin structure infections, uncomplicated pneumonia 750 mg 8 hrly. Dose may be doubled in severe infections of the bone & joint.
Life-threatening infections 1.5 g 6 hrly.
Bacterial meningitis Max: 3 g 8 hrly.
Uncomplicated gonorrhoea Single dose of 1.5 g IM w/ 1 g probenecid.
Disseminated gonococcal infections 750 mg 8 hrly.
Peri-op prophylaxis 1.5 g IV 30-60 min before op & 750 mg IM/IV 8 hrly.
Open heart surgery A single 1.5 g dose IV during induction of anesth & 12 hrly for a total dose of 6 g.
Childn ≥3 mth 50-100 mg/kg/day in divided doses.
Bone & joint infections in childn 150 mg/kg/day.
Bacterial meningitis 200-240 mg/kg/day.