Ovidrel Adverse Reactions

In comparative trials with different doses of Ovidrel, the undesirable effects listed as follows were found to be associated with Ovidrel in a dose-related fashion: Ovarian hyperstimulation syndrome, and vomiting and nausea. Ovarian hyperstimulation syndrome was observed in approximately 4% of patients treated with Ovidrel. Severe ovarian hyperstimulation syndrome was reported in <0.5% patients (see Precautions).
In rare instances, thromboembolisms have been associated with menotrophin/hCG therapy. Although this adverse event was not observed, there is the possibility that this may also occur with Ovidrel.
Ectopic pregnancy, ovarian torsion and other complications have been reported in patients after hCG administration. These are considered concomitant effects related to assisted reproductive technologies (ART).
After best evidence assessment, the undesirable effects listed as follows may be observed after administration of Ovidrel.
Common (>1/100, <1/10): Application Site Disorders: Local reaction/pain at injection site.
General Disorders: Headache, tiredness.
Gastrointestinal System Disorders: Vomiting/nausea, abdominal pain.
Reproductive Disorders: Mild or moderate ovarian hyperstimulation syndrome.
Uncommon (>1/1000, <1/100): Psychiatric Disorders: Depression, irritability, restlessness.
Gastrointestinal System Disorders: Diarrhea.
Reproductive Disorders: Severe ovarian hyperstimulation syndrome, breast pain.