Reduction in the duration of neutropenia & the incidence of febrile neutropenia in patients treated w/ established cytotoxic chemotherapy for non-myeloid malignancy.
Dosage/Direction for Use
Recommended starting dose: 5 mcg/kg/day SC bolus or short IV infusion or by continuous SC or IV infusion. Should not be used <24 hr after & prior to chemotherapy. Cancer patient receiving bone marrow transplant; peripheral blood progenitor cell collection & therapy in cancer patient 10 mcg/kg/day.
Contraindications
Hypersensitivity to E. coli-derived proteins, filgastrim or G-CSF products.
Special Precautions
Avoid simultaneous use w/ chemotherapy & RT. Perform CBC twice wkly during therapy. Pregnancy & lactation.
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