Dose range: 150-600 mg daily given in 2 or 3 divided doses.
Neuropathic pain Recommended starting dose: 75 mg twice daily. May be increased to 150 mg twice daily after 3-7 days & if needed, to a max dose of 300 mg twice daily after an additional wk.
Epilepsy Recommended starting dose: 75 mg twice daily. May be increased to 150 mg twice daily after 1 wk & if needed, to a max dose of 300 mg twice daily after an additional wk.
Patient w/ CrCl ≥60 mL/min Starting dose: 150 mg twice daily. Max: 600 mg twice daily,
30-60 mL/min Starting dose: 75 mg once or twice daily. Max: 300 mg once or twice daily,
15-30 mL/min Starting dose: 25-30 mg once or twice daily. Max: 150 mg once or twice daily,
<15 mL/min Starting dose: 25 mg once daily. Max: 75 mg once daily. Supplementary dose following hemodialysis: Initially 25 mg single dose. Max: 100 mg single dose.