Mesol Dosage & Drug Information

Concise Prescribing Info Bahasa Concise Prescribing Info

Concise Prescribing Info

Contents

Methylprednisolone

Indications/Uses

Endocrine disorders, rheumatic disorders, collagen disease, skin diseases, bronchial asthma, atopic dermatitis; ophth, resp & GI diseases; hematological disorders, neoplastic disease, edematous states, acute exacerbation of multiple sclerosis.

Dosage/Direction for Use

Tab Initially 4-48 mg daily. Multiple sclerosis 160 mg daily for some wk, followed by 64 mg daily for 1 mth. IM/IV inj Adult 10-40 mg, repeat as needed. Childn 139-835 mcg (0.139-0.835 mg)/kg IM 12-24 hrly. Adrenocortical insufficiency 117 mcg (0.117 mg)/kg IM in 3 divided doses every 3rd day.

Administration

Should be taken with food.

Contraindications

Systemic fungal infections, gastric ulcer, osteoporosis, psychiatric disorders, amoebiasis, poliomyelitis, narrow- or open-angle glaucoma, viral infections.

Special Precautions

Prolonged use (especially in babies & childn). Nonspecific ulcerative colitis, diverticulitis intestinal anastomoses, active or latent peptic ulcer, renal insufficiency, HTN, osteoporosis, myasthenia gravis. Concomitant use w/ ASA in patients w/ hypoprothrombinemia. Hypothyroidism, cirrhosis, diabetes. Pregnancy & lactation.

Adverse Reactions

Electrolyte & fluid imbalances, musculoskeletal disorder, peptic ulcer associated w/ bleeding & perforation, pancreatitis, abdominal distension, ulcerative esophagitis, skin diseases, convulsion, increased ICP w/ papilloedema, vertigo, headache, seizure, pseudotumor cerebri, endocrine disturbances, posterior silocapsular cataract, increased IOP, glaucoma, exophthalmus, -ve nitrogen balance due to protein catabolism, hypersensitivity reactions.

View ADR Monitoring Form

Drug Interactions

Cardiac glycosides, diuretics, antidiabetic agents, coumarin derivatives, rifampicin, phenytoin, barbiturates, aspirin, cyclosporine, ketoconazole, troleandomycin.

MIMS Class

Corticosteroid Hormones

ATC Classification

H02AB04 - methylprednisolone ; Belongs to the class of glucocorticoids. Used in systemic corticosteroid preparations.

Regulatory Classification

Presentation/Packing

Form

Mesol powd for inj 125 mg

Packing/Price

(+ amp (2 mL solvent)) 1's

Form

Mesol tab 16 mg

Packing/Price

3 × 10's

Form

Mesol tab 4 mg

Packing/Price

3 × 10's

Form

Mesol tab 8 mg

Packing/Price

3 × 10's

Mesol

methylprednisolone

Manufacturer:

Gracia Pharmindo