Synergistic effects w/ ceftazidime, metronidazole, ciprofloxacin. Prevent bactericidal activity of aminoglycosides. Abrasive, cleansing agents, acne or any prep containing peeling agents eg, resorcinol, salicylic acid, sulfur. Topical alcohol prep eg, after-shave lotions, astringents, perfumed toiletries, shaving cream/lotion. May prolong effect of neuromuscular blocking agents. Antagonize effects w/ erythromycin.