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Patients with renal impairment should be given a lower initial dose, because it may decrease clearence potential of Loratadine, the recommended initial dose is 5 mg once a day or 10 mg every two days.
Safety and efficacy of Loratadine in children under 2 years old have not been established.
Do not use Loratadine during pregnancy unless the potential benefit justifies the potential risk to fetus.
Should not be recommended to lactating women because it will be excreted to the breast milk.
