Reducing plasma ammoniac level in condition of hyperammonemia as a result of acute & chronic liver disease eg, liver cirrhosis, fatty liver, hepatitis especially in the treatment of pre-coma or neurological complications (hepatic encephalopathy).
Dosage/Direction for Use
Granules for oral soln 3 sachet/day. Inj 4 amp/day. Pre-coma or coma 8 amp may be given w/in 24 hr depending on the severity of the condition. Max infusion rate: 5 g/hr.
Administration
Should be taken with food.
Contraindications
Oral soln/inj: Severe renal impairment. Inj: Administration via artery.
Special Precautions
Monitor serum & urine urea levels at high doses. Impaired liver function. May impair ability to drive or operate machinery. Pregnancy & lactation.
Adverse Reactions
Mild to moderate vomiting, nausea, sensation of heat & palpitation.
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