Lapirom Dosage & Drug Information

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Concise Prescribing Info

Contents

Cefpirome

Indications/Uses

Lower resp tract infections (bronchopneumonia & lobar pneumonia), complicated upper & lower UTI (pyelonephritis), cellulitis, skin abscess, wound infections, infections in neutropenic & immunocompromised patients.

Dosage/Direction for Use

Complicated upper & lower UTI, skin & soft tissue infections, lower resp tract infections 1 g 12 hrly. Max: 2 g/day. Bacteremia/septicemia, severe infections or infections in patient w/ neutropenia 2 g 12 hrly. Max: 4 g/day.

Contraindications

History of hypersensitivity to β-lactams. Sensitivity to penicillin.

Special Precautions

Hypersensitivity to penicillin. May cause pseudomembranous colitis & cross-sensitivity w/ penicillin. Monitor blood count in prolonged treatment (>10 days). Renal impairment. Pregnancy & lactation.

Adverse Reactions

Hypersensitivity reactions, GI effects, interstitial nephritis, increased liver enzyme, haematological changes, thrombophlebitis, pain at inj site, convulsion, reversible encephalopathy, superinfections.

View ADR Monitoring Form

Drug Interactions

Aminoglycosides, diuretics, probenecid; false +ve in Coombs' test; may cause creatinine-like reactions in creatinine test using picrate method.

MIMS Class

Cephalosporins

ATC Classification

J01DE02 - cefpirome ; Belongs to the class of fourth generation cephalosporins. Used in the systemic treatment of infections.

Regulatory Classification

Presentation/Packing

Form

Lapirom powd for inj 1 g

Packing/Price

1's

Lapirom

cefpirome

Manufacturer:

Lapi