Inflason

Prednisone

Inflammatory & allergic conditions which need glucocorticoid treatment eg, rheumatic, collagen disease, skin disease.

Adult 1-4 caplet daily.

Should be taken with food.

Peptic ulcer, active TB, osteoporosis, neurological disorders, kidney & heart disease. Systemic fungal infection, ocular herpes simplex.

Avoid abrupt w/drawal in long-term use. Childn during growth period. Prolonged use. Diabetes, hypothyroid, cirrhosis, heart failure, disease due to infection, chronic renal failure. Pregnancy, lactation. Elderly.

Na & fluid retention, K loss, alkalosis, hypokalemia, HTN, CHF. Muscle weakness, steroid myopathy, loss of muscle mass, osteoporosis, vertebral compression fracture, pathologic fracture of long bone. Peptic ulcer w/ possibility to perforation & bleeding, pancreatitis, abdominal distension, ulcerative oesophagitis. Delayed wound healing, thin skin, facial erythema, sweating. Convulsion, increase ICP w/ papilledema, vertigo, headache. Irregular menstrual period, growth retardation, secondary adrenocorticoid, non-responsive pituitary, reduce carbohydrate tolerance. Posterior subcapsular cataract, increase IOP, glaucoma, exophthalmos. -ve nitrogen balance. Anaphylactic reaction.

Acetosal, rifampicin, phenytoin, phenobarb, vaccination.

Corticosteroid Hormones

H02AB07 - prednisone ; Belongs to the class of glucocorticoids. Used in systemic corticosteroid preparations.

G