Inclisiran - subcutaneous

Patient Medicine Information
Why do I need this medicine?
Inclisiran may be used on its own or together with other medicines to help lower your cholesterol and triglyceride (fat) levels in the blood.

Excessive cholesterol and triglycerides in your body can clog up your blood vessels. This can lead to many health problems such as stroke and heart diseases, including heart attack.

This medicine is meant to be used as part of a complete cholesterol management programme that should include exercise, a healthy diet and lifestyle.

Inclisiran may be used to treat other conditions as decided by your doctor.
How do I use this medicine?
Inclisiran is to be injected subcutaneously (into the fatty layer under the skin, usually in the abdomen area, upper arm, or thigh).

Your doctor or nurse will administer the injection for you.

Do not inject into areas with active skin disease or injury such as skin rashes, inflammation, sunburn or skin infection.
What should I do if I have forgotten to use this medicine?
Ensure that you keep all appointments with your doctor so that you do not miss any doses. Your doctor also needs to regularly monitor your response to Inclisiran.

If you miss an appointment or miss an injection, alert your doctor or nurse. A replacement appointment or injection should be given as soon as possible.
What should I take note of while using this medicine?
Inform your doctor if you have the following conditions:
  • severe liver disease
  • severe kidney disease or undergoing dialysis
Let your doctor know if you are pregnant or breastfeeding.

For as long as you are being treated with Inclisiran, you may need to have regular blood tests (e.g. cholesterol levels) to check your body's response to the medicine. Your doctor will advise you about how often you need to have blood tests.

What lifestyle changes should I make to reduce my cholesterol levels?

A healthy, balanced diet and regular exercise are keys to help you reduce your cholesterol levels. Try to control the type and amount of food that you eat each meal. Include lots of fruits and vegetables in your diet, and avoid eating fried foods or foods that are high in fat. If you have not been exercising, start slow and gradually step up your exercise capacity.
What side effects could I experience?
Inclisiran may cause any of the following side effects: headaches, dizziness, cough, cold, diarrhoea, joint or back pain, and injection site pain, redness or rash.

Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I use this with other medicines?
Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
Store in a cool, dry place away from the reach of children. Do not freeze.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on inclisiran - subcutaneous and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2024 MIMS. All rights reserved. Powered by
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