Patients w/ history of ocular herpes. Carefully monitor patients w/ severe keratitis. Remove contact lenses prior to instillation at bedtime (may reinsert at wake-up time). Concomitant therapy w/ β-blockers in patients w/ glaucoma. May affect host defenses against infections & malignancies. Co-administration with eye drops containing corticosteroids. May cause eye irritation due to cetalkonium Cl content. Moderate influence on the ability to drive & use machines (may induce temporary blurred vision or other visual disturbances). Not recommended in women of childbearing potential not using effective contraception. Not recommended during pregnancy. Lactation.