Initially 150 mg/kg bolus dose for 60 min, at least 200 mL in adult & 50 mL in childn. Subsequent 50 mg/kg doses should be given at slow infusion rate 4 hrly for 72 hr.
Anaphylactic reactions may occur if directly administered at high dose & fast rate. Monitor patients w/ bronchial asthma or history of asthma for occurrence of bronchospasm.
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