Fovepta Dosage/Direction for Use

Posology: Prevention of hepatitis B in the newborn, of a hepatitis B virus carrier-mother, at birth or as soon as possible after birth (at latest within 12 hours): 200 IU.
The hepatitis B immunoglobulin administration may need to be repeated until seroconversion following vaccination.
In all these situations, vaccination against hepatitis B virus is highly recommended. The first vaccine dose can be injected the same day as human hepatitis B immunoglobulin, however in different sites. In subjects who did not show an immune response (no measurable hepatitis B antibodies) after vaccination, and for whom continuous prevention is necessary, administration of 8 IU/kg to children every 2 months can be considered; a minimum protective antibody titre is considered to be 10 mIU/mL.
Method of administration: Fovepta should be administered via the subcutaneous or the intramuscular route.
If intramuscular administration is contraindicated (bleeding disorders), the injection can be administered subcutaneously.
Where simultaneous vaccination is necessary, the immunoglobulin and the vaccine should be administered at two different sites.