Euthyrox Dosage/Direction for Use

The individual daily dose should be determined by laboratory tests and clinical examinations. Particular caution must be exercised when starting treatment with thyroid hormones in elderly patients, patients with coronary heart disease and patients with severe or long-standing hypothyroidism, that is, a small dose should be chosen to start with which can then be increased gradually and at long intervals with frequent thyroid hormone checks. Experience has shown that a small dose is also sufficient for patients with a low body weight and patients with a large nodular goitre.
Goitre (Euthyroid Goitre): Adults: 75-200 mcg once daily. Adolescents: 50-150 mcg once daily.
Prevention of Goitre Recurrence After Goitre Surgery  (Strumectomy): 75-200 mcg once daily.
Hypothyroidism in Adults at the Start of Therapy: 25-50 mcg once daily (increase by 25-50 mcg at 2- to 4-weekly intervals). Maintenance Therapy: 125-250 mcg once daily.
Children: Start of therapy: 12.5-50 mcg once daily. Maintenance therapy: 100-150 mcg/m² body surface once daily.
Concomitant Therapy with Medication Against Hyperthyroidism: 50-100 mcg once daily.
After Total Surgical Removal of the Thyroid (Thyroidectomy): 150-300 mcg once daily.
Thyroid Suppression Test: 200 mcg once daily.
In children with a sound heart, the therapy may be started with the entire dose. In adults, the therapy has to be started using small initial doses and gradually increasing to optimum amounts.
The entire daily dose of Euthyrox should be taken in the morning on an empty stomach, at least half an hour before breakfast with some liquid (ie, half a glass of water). The duration of treatment is generally for life in hypothyroidism and after surgical removal of part or all of the thyroid gland, for some months up to life in the treatment of goitre (euthyroid goitre) and in prevention of goitre recurrence (goitre relapse prophylaxis). In concomitant therapy to treat hyperthyroidism for as long as the drug against hyperthyroidism is taken.
Thyroid Suppression Test: 14 days before the repeat scan.