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No evidence exist that indicates that treatment with Erythropoietin alfa alters the metabolism of other drugs. Drugs that decrease erythropoiesis may decrease the response to Erythropoietin alfa.
No evidence exist that indicates an interaction between Erythropoietin alfa and G-CSF or GM-CSF with regard to haematological differentiation or proliferation of tumour cells from biopsy specimens in vitro.
The effect of Erythropoietin alfa may be potentiated by the simultaneous therapeutic administration of a haematinic agents, such as ferrous sulphate, when a deficiency state exist.
