Budenofalk Drug Interactions

Cardiac glycosides: Hypokalemia may increase the effect of glycosides.
Diuretics: The potassium excretion may be increased.
Cytochrome P-450 inhibitors (eg, ketoconazole, troleandomycin, ethinylestradiol, erythromycin, cyclosporine): The corticoid effect may be increased.
The simultaneous administration of cimetidine and budesonide may lead to a slight increase of the budesonide plasma level, which is of no clinical relevance. The simultaneous administration of omeprazole does not change the pharmacokinetics of budesonide.
Possible interactions with steroid-binding synthetic resins eg, cholestyramine and antacids cannot be excluded. Therefore, during simultaneous intake of Budenofalk, the effect of budesonide may be decreased. Therefore, these drugs should be administered with at least 2 hrs interval.