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Posology (tablet): The starting and recommended dose of Brintellix is 10 mg vortioxetine once daily in adults less than 65 years of age.
Depending on individual patient response, the dose may be increased to a maximum of 20 mg vortioxetine once daily or decreased to a minimum of 5 mg vortioxetine once daily.
Treatment discontinuation: Patients treated with vortioxetine can abruptly stop taking the medicinal product without the need for a gradual reduction in dose (see Pharmacology: Pharmacodynamics under Actions).
Special population: Elderly patients: The lowest effective dose of 5 mg vortioxetine once daily should always be used as the starting dose in patients ≥ 65 years of age. Caution is advised when treating patients ≥ 65 years of age with doses higher than 10 mg vortioxetine once daily for which data are limited (see Precautions).
Method of administration: Brintellix is for oral use.
The film-coated tablets can be taken with or without food.
