Baxcef

Baxcef

cefoperazone + sulbactam

Manufacturer:

Solas
Concise Prescribing Info
Contents
Sulbactam Na 500 mg, cefoperazone Na 500 mg
Indications/Uses
Upper & lower resp tract infection, UTI, peritonitis, cholecystitis, cholangitis, & other intra-abdominal infections, skin & soft tissue infections.
Dosage/Direction for Use
Adult 2-4 g daily 12 hrly. May be increased up to 8 g daily in severe or refractory infections. Max daily dose: 4 g. Childn 40-80 mg/kg/day in divided doses every 6-12 hr. May be increased up to 160 mg/kg/day in severe or refractory administered in 2-4 equally divided doses. Neonate May be given in the 1st wk of life 12 hrly. Max: 80 mg/kg/day.
Contraindications
Hypersensitivity to penicillins, sulbactam, cefoperazone or any of the cephalosporins.
Special Precautions
Vit K deficiency in patient w/ poor diet, malabsorption states (cystic fibrosis) & prolonged IV alimentation regimen. Monitor prothrombin time & those receiving anticoagulant therapy. Overgrowth of nonsusceptible organism in prolonged use. Periodic monitoring for organ system dysfunction during extended therapy eg, renal, hepatic & hematopoietic system. May impair ability to drive or operate machinery. Pregnancy & lactation. Childn.
Adverse Reactions
Diarrhea, nausea, vomiting, maculopapular rash, urticaria, drug fever, reversible neutropenia, decreased Hb or hematocrit, transient eosinophilia, thrombocytopenia, hypoprothrombinemia, haemolytic anemia, headache, fever, inj pain, chills, transient elevation of SGOT, SGPT, alkaline phosphatase, & bilirubin level.
Drug Interactions
Alcohol, false +ve reaction in the urine may occur w/ Benedict's or Fehling's soln.
MIMS Class
Cephalosporins
ATC Classification
J01DD62 - cefoperazone and beta-lactamase inhibitor ; Belongs to the class of third-generation cephalosporins. Used in the systemic treatment of infections.
Presentation/Packing
Form
Baxcef inj
Packing/Price
1 g x 1's (Rp180,000/boks)
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