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Pharmacology: Propofol is a short-acting general anesthetic agent with a rapid onset of action of approximately 30 seconds.
The duration of anesthesia depending on the metabolism and elimination is 4 to 6 minutes. During monitored anesthesia care sedation, attention must be given to the cardiorespiratory effect of Propofol. Hypotension, oxyhemoglobin desaturation, apnea, airway obstruction and/or oxygen desaturation can occur following a rapid bolus or rapid increases of Propofol. Propofol lack vagolytic activity and has been associated with reports of bradycardia and asystole.
