Lokelma

Generic Name : Sodium zirconium cyclosilicate

Indication : Hyperkalaemia.

Manufacturer : AstraZeneca

Distributor : Four Star / Zuellig

MIMS Class : Other Therapeutic Products

Sodium zirconium cyclosilicate

Mechanism of Action

Description:
Mechanism of Action: Sodium zirconium cyclosilicate, a non-absorbed cation-exchange compound, acts as a selective K binder by preferentially exchanging K for hydrogen and Na cations. This activity ...

Lokelma Drug Interactions

...Changes in solubility & absorption kinetics of co-administered medicinal products w/ pH-dependent bioavailability [eg, azole antifungals (ketoconazole, itraconazole & posaconazole), anti-HIV...

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