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Instructions on how to use Xultophy 100 units/ml + 3.6 mg/ml solution for injection: Please read these instructions carefully before using your Xultophy pre-filled pen.
Do not use the pen without proper training from your doctor or nurse.
Start by checking your pen to make sure that it contains Xultophy 100 units/ml + 3.6 mg/ml.
If you are blind or have poor eyesight and cannot read the dose counter on the pen, do not use this pen without help. Get help from a person with good eyesight who is trained to use the Xultophy pre-filled pen.
Xultophy is a medicine that contains insulin degludec and liraglutide. Xultophy is administered as dose steps. One dose step contains 1 unit insulin degludec + 0.036 mg liraglutide.
Your pen is a pre-filled dial-a-dose pen. It contains 3 ml of Xultophy solution. It delivers doses from: 1 dose step; to a maximum of 50 dose steps (50 units insulin degludec + 1.8 mg liraglutide).
Your pen delivers doses in increments of 1 dose step. Do not do any conversion of your dose. The dose steps dialled equal the number shown in the dose counter.
Your pen is designed to be used with NovoTwist or NovoFine disposable needles up to a length of 8 mm and as thin as 32G. Needles are not included in the pack.
1. Prepare your pen with a new needle: A. Check the name and coloured label of your pen, to make sure that it contains Xultophy.
This is especially important if you take more than one type of injectable medicine.
Taking the wrong medicine could be harmful to your health.
Pull off the pen cap.
B. Check that the solution in your pen is clear and colourless. Look through the pen window. If the solution looks cloudy, do not use the pen.
C. Take a new needle, and tear off the paper tab.
D. Push the needle straight onto the pen. Turn until it is on tight.
E. Pull off the outer needle cap and keep it for later. You will need it after the injection, to safely remove the needle from the pen.
F. Pull off the inner needle cap and throw it away. If you try to put it back on, you may accidentally stick yourself with the needle.
A drop of solution may appear at the needle tip. This is normal, but you must still check the flow.
Do not attach a new needle to your pen until you are ready to take your injection.
Always use a new needle for each injection. This may prevent blocked needles, contamination, infection and inaccurate dosing.
Never use a bent or damaged needle.
2. Check the flow: A. Turn the dose selector to select 2 dose steps. Make sure the dose counter shows 2.
The dose counter and the dose pointer show how many dose steps of Xultophy you select.
B. Hold the pen with the needle pointing up.
Tap the top of the pen gently a few times to let any air bubbles rise to the top.
C. Press and hold in the dose button until the dose counter returns to 0. The 0 must line up with the dose pointer.
A drop of solution should appear at the needle tip.
A small drop may remain at the needle tip, but it will not be injected.
If no drop appears, repeat steps 2A to 2C up to 6 times. If there is still no drop, change the needle and repeat steps 2A to 2C once more.
If a drop of solution still does not appear, dispose of the pen and use a new one.
Always make sure that a drop appears at the needle tip before you inject. This makes sure that the solution flows.
If no drop appears, you will not inject any medicine, even though the dose counter may move. This may indicate a blocked or damaged needle.
It is important always to check the flow before you inject. If you do not check the flow, you may get too little medicine, or no medicine at all. This may lead to high blood sugar level.
3. Select your dose: A. Turn the dose selector to select the dose you need.
The dose counter shows the dose in dose steps. If you select a wrong dose, you can turn the dose selector forward or backward to the correct dose.
The pen can dial up to a maximum of 50 dose steps.
The dose selector changes the number of dose steps.
Only the dose counter and dose pointer will show how many dose steps you select per dose. You can select up to 50 dose steps per dose. When your pen contains less than 50 dose steps, the dose counter stops at the number of dose steps left.
The dose selector clicks differently when turned forward, backward or past the number of dose steps left. Do not count the pen clicks.
Always use the dose counter and the dose pointer to see how many dose steps you have selected before injecting the medicine.
Do not count the pen clicks. If you select and inject the wrong dose, your blood sugar level may get high or low.
Do not use the pen scale, it only shows approximately how much solution is left in your pen.
How much solution is left?: The pen scale shows you approximately how much solution is left in your pen.
To see precisely how much solution is left, use the dose counter: Turn the dose selector until the dose counter stops.
If it shows 50, at least 50 dose steps are left in your pen. If it shows less than 50, the number shown is the number of dose steps left in your pen.
If you need more medicine than what is left in your pen, you can split your dose between two pens.
Be very careful to calculate correctly if splitting your dose.
If in doubt, take the full dose with a new pen. If you split the dose wrongly, you will inject too little or too much medicine. This may make your blood sugar level high or low.
4. Inject your dose: A. Insert the needle into your skin as your doctor or nurse has shown you.
Make sure you can see the dose counter. Do not cover it with your fingers. This could interrupt the injection.
B. Press and hold down the dose button until the dose counter shows 0.
The 0 must line up with the dose pointer. You may then hear or feel a click.
C. Keep the needle in your skin after the dose counter has returned to 0 and count slowly to 6.
If the needle is removed earlier, you may see a stream of solution coming from the needle tip. If so, the full dose will not be delivered, and you should increase the frequency of checking your blood sugar level.
D. Remove the needle from your skin.
If blood appears at the injection site, press lightly. Do not rub the area.
You may see a drop of solution at the needle tip after injecting. This is normal and does not affect your dose.
Always watch the dose counter to know how many dose steps you inject. Hold the dose button down until the dose counter shows 0. If the dose counter does not return to 0, the full dose has not been delivered, which may lead to high blood sugar level.
How to identify a blocked or damaged needle?: If 0 does not appear in the dose counter after continuously pressing the dose button, you may have used a blocked or damaged needle.
In this case - you have not received any medicine - even though the dose counter has moved from the original dose that you have set.
How to handle a blocked needle?: Change the needle as described in section '5. After your injection' as follows and repeat all steps starting with section '1. Prepare your pen with a new needle'. Make sure you select the full dose you need.
Never touch the dose counter when you inject. This can interrupt the injection.
5. After your injection: A. Lead the needle tip into the outer needle cap on a flat surface without touching the needle or the outer cap.
B. Once the needle is covered, carefully push the outer needle cap completely on.
Unscrew the needle and dispose of it carefully as instructed by your doctor or nurse.
C. Put the pen cap on your pen after each use to protect the solution from light.
Always dispose of the needle after each injection to ensure the use of a sharp needle and prevent blocked needles. If the needle is blocked, you will not inject any medicine.
When the pen is empty, throw it away without a needle on as instructed by your doctor, nurse, pharmacist or local authorities.
Never try to put the inner needle cap back on the needle. You may stick yourself with the needle.
Always remove the needle from your pen after each injection.
This may prevent blocked needles, contamination, infection, leakage of solution and inaccurate dosing.
Further important information: Always keep an extra pen and new needles, in case of loss or damage.
Always keep your pen and needles out of sight and reach of others, especially children.
Never share your pen with other people. Your medicine might be harmful to their health.
Never share your needles with other people. It might lead to cross-infection.
Caregivers must be very careful when handling used needles - to prevent needle injury and cross-infection.
Caring for your pen: Do not leave the pen in a car or other place where it can get too hot or too cold.
Do not store your pen at temperatures above 30°C.
Do not expose your pen to dust, dirt or liquid.
Do not wash, soak or lubricate your pen. If necessary, clean it with mild detergent on a moistened cloth.
Do not drop your pen or knock it against hard surfaces.
If you drop it or suspect a problem, attach a new needle and check the flow before you inject.
Do not try to refill your pen. Once empty, it must be disposed of.
Do not try to repair your pen or pull it apart.
