Xenical Dosage/Direction for Use

Standard Dosage: Recommended Dose: 1 cap which should be taken immediately before, during or up to 1 hr after each main meal. If a meal is missed or contains no fat, the dose of orlistat should be omitted.
The patient should be on a nutritionally balanced, mildly hypocaloric diet that contains approximately 30% of calories from fat. It is recommended that the diet should be rich in fruit and vegetables. The daily intake of fat, carbohydrate and protein should be distributed over 3 main meals.
Doses of orlistat >120 mg 3 times daily have not been shown to provide additional benefit. The effect of orlistat results in an increase in fecal fat as early as 24-48 hrs after dosing. Upon discontinuation of therapy, fecal fat content usually returns to pre-treatment levels, within 48-72 hrs.
Special Populations: The effect of orlistat in patients with hepatic and/or renal impairment has not been studied. Orlistat is not intended to be used in children.