Discontinue treatment if anaphylactic reactions &/or angioedema w/ airway obstruction occur. Patients suffering from bladder obstruction or difficulty in passing urine (eg, thin urine flow); constipation; at risk of digestive system slowing down (stomach & bowel movements); severe kidney disease; moderate liver disease; stomach tear (hiatus hernia) or heartburn; autonomic neuropathy. Patients w/ risk factors for QT prolongation eg, pre-existing abnormal ECG & high K levels. Do not use in patients w/ rare hereditary problem of galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption. May affect ability to drive or operate machinery. Pregnancy. Do not use if breast-feeding. Do not use in childn or adolescents <18 yr.