Verorab

Verorab

rabies vaccine

Manufacturer:

Sanofi

Distributor:

Zuellig
/
Four Star
Concise Prescribing Info
Contents
Inactivated rabies vaccine
Indications/Uses
Pre- & post-exposure rabies prophylaxis in all age groups.
Dosage/Direction for Use
IM Recommended dose: 0.5 mL of reconstituted vaccine. Pre-exposure prophylaxis Immunocompetent individual or individual w/ decreased immunity Conventional regimen: 1 dose on day 0, 7, & 21 or 28. Immunocompetent individual 1-wk regimen: 1 dose on day 0 & 7. Post-exposure prophylaxis Non-immunised subject or individual w/ decreased immunity Essen protocol: 1 dose on day 0, 3, 7, 14, & 28. Zagreb protocol: 2 doses on day 0; 1 dose on day 7 & 21. Immunised subject 1 dose on day 0 & 3. ID Recommended dose: 0.1 mL of reconstituted vaccine per inj site. Pre-exposure prophylaxis Immunocompetent individual 1-wk regimen: 2 doses on day 0 & 7. Post-exposure prophylaxis Non-immunised subject or individual w/ decreased immunity New Thailand Red Cross ID regimen: 2 doses on day 0, 3, 7, & 28. Institute Pasteur of Cambodia ID regimen: 2 doses on day 0, 3, & 7. 4-site 1-wk ID regimen: 4 doses on day 0, 3, & 7. Immunised subject 1 dose on day 0 & 3. Alternatively, 4 doses at 4 separate sites on day 0.
Contraindications
Pre-exposure: Hypersensitivity. Presence of fever or acute disease.
Special Precautions
Do not administer via intravascular route. Appropriate medical treatment & supervision must be readily available in case of a rare anaphylactic reaction after vaccine administration. Caution in individuals w/ allergy to polymyxin B, streptomycin, neomycin or to any antibiotic of the same class. Perform serological tests in accordance w/ official recommendations. In case of immunodeficiency, perform blood tests 2-4 wk after vaccination to ensure protective immune response was obtained. Risk of bleeding during IM administration in subjects w/ thrombocytopenia or clotting disorders. Contains phenylalanine; may be harmful to phenylketonurics. Can temporarily affect ability to drive & use machines.
Adverse Reactions
Generally feeling unwell; headache; muscle pain; pain, erythema, &/or swelling at the inj site; (only in babies) irritability, inconsolable crying & drowsiness. Fever; lymphadenopathy; allergic reactions eg, rash & itching; flu-like syndrome; pruritus &/or induration at the inj site; (only in babies) difficulty sleeping.
Drug Interactions
Corticosteroids & immunosuppressives may interfere w/ Ab production. Do not combine rabies Ig & rabies vaccine in the same syringe or administer at the same site.
MIMS Class
Vaccines, Antisera & Immunologicals
ATC Classification
J07BG01 - rabies, inactivated, whole virus ; Belongs to the class of rabies viral vaccines.
Presentation/Packing
Form
Verorab vaccine (inj)
Packing/Price
(vial) 1 dose x 1's
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