Herpes & ophth zoster Immunocompetent adult 1,000 mg tds for 7 days.
Immunocompromised adult 1,000 mg tds for at least 7 days & for 2 days following crusting of lesions.
HSV infection Immunocompetent adult & adolescent ≥12 yr 500 mg bd for 3-5 days for recurrent episodes. Treatment may be extended to 10 days for initial, more severe episodes.
Immunocompromised adult 1,000 mg bd for at least 5 days; may have to be extended to 10 days for initial, more severe episodes.
Herpes labialis 2,000 mg bd for 1 day. Take 2nd dose about 12 hr after the 1st dose.
Suppression of recurrence of HSV infection Immunocompetent adult & adolescent ≥12 yr 500 mg once daily.
Immunocompromised adult 500 mg bd.
Prophylaxis of CMV infection & disease 2,000 mg qds.
Renal impairment Reduce dose according to CrCl.
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