Vagifem Dosage/Direction for Use

Vagifem is administered intravaginally as local oestrogen therapy by use of an applicator.
Initial dose: One vaginal tablet daily for 2 weeks.
Maintenance dose: One vaginal tablet twice a week.
Treatment may start on any convenient day.
If a dose is forgotten, it should be taken as soon as the patient remembers. A double dose should be avoided.
For initiation and continuation of treatment of postmenopausal symptoms, the lowest effective dose for the shortest duration (see Precautions) should be used.
Vagifem is a local vaginal therapy and in women with an intact uterus, progestagen treatment is not necessary (see Endometrial hyperplasia and carcinoma under Precautions).
Vagifem may be used in women with or without an intact uterus.
Vaginal infections should be treated before start of the Vagifem therapy.
Administration: 1. Open the blister pack at the plunger end.
2. Insert the applicator in the vagina until resistance is met (8-10 cm).
3. Release the tablet by pressing the plunger.
4. Withdraw the applicator and discard.