Treatment of haemorrhage, or threatened haemorrhage associated w/ excessive fibrinolysis. Management of haemophiliacs undergoing dental extractions. Prophylaxis of hereditary angioedema.
Not indicated in hematuria caused by diseases of the renal parenchyma. Increased risk of clotting in patients w/ underlying thrombotic states. Give in reduced doses to patient w/ renal impairment. Lactation.
Increased potential for thrombus formation w/ OCs or estrogen-containing medication. Concurrent use w/ Factor IX complex may increase risk of thrombotic complication in perisurgical management of hemophilic patients.
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