Tremfya Patient Counseling Information

Instructions for use: Important: If your doctor decides that you or a caregiver may be able to give your injections of Tremfya at home, you should receive training on the right way to prepare and inject Tremfya using the pre-filled pen.
Please read these Instructions for use before using the Tremfya pre-filled pen and each time you get a new pre-filled pen. There may be new information. This instruction guide does not take the place of talking with your doctor about your medical condition or your treatment.
Please also read the Package Leaflet carefully before starting your injection and discuss any questions you may have with your doctor or nurse.
Call your doctor to talk about any questions you may have. For additional assistance or to share your feedback refer to the Package Leaflet for your local representative contact information.
You will need these supplies: 1 alcohol swab, 1 cotton ball or gauze pad, 1 adhesive bandage, 1 sharps container (see Step 3 as follows).
1. Prepare for your injection.
Inspect carton: Remove carton with the pre-filled pen from the refrigerator. Keep pre-filled pen in the carton and let it sit on a flat surface at room temperature for at least 30 minutes before use. Do not warm any other way. Check the expiration date ('EXP') on the carton. Do not use if the expiration date has passed. Do not inject if perforations on the carton are broken. Call your doctor or pharmacist for a new pre-filled pen.
Choose injection site: Select from the following areas for your injection: Front of thighs (recommended); Lower abdomen (do not use the 5-centimetre area around your belly-button); Back of upper arms (if a caregiver is giving you the injection). Do not inject into skin that is tender, bruised, red, scaly, hard or has scars or stretch marks.
Wash hands: Wash your hands well with soap and warm water.
Clean injection site: Wipe your chosen injection site with an alcohol swab and allow it to dry. Do not touch, fan or blow on the injection site after you have cleaned it.
Inspect liquid in window: Take the pre-filled pen out of the carton. Check the liquid in the window. It should be clear to slightly yellow and may contain tiny white or clear particles. You may also see one or more air bubbles. This is normal. Do not inject if the liquid is cloudy or discoloured, or has large particles. If you are uncertain, call your doctor or pharmacist for a new pre-filled pen.
2. Inject Tremfya using the pre-filled pen.
Twist and pull off bottom cap: Keep hands away from the needle guard after the cap is removed. Inject within 5 minutes of removing the cap. Do not put the cap back on, this could damage the needle. Do not use the pre-filled pen if it is dropped after removing the cap. Call your doctor or pharmacist for a new pre-filled pen.
Place on skin: Position the pre-filled pen straight onto the skin (about 90 degrees relative to injection site).
Push handle straight down: Medication injects as you push. Do this at a speed that is comfortable for you. Do not lift the pre-filled pen during the injection. The needle guard will lock and the full dose will not be delivered.
Complete injection: Injection is complete when the handle is pushed all the way down, you hear a click, and the green body is no longer visible.
Lift straight up: The yellow band indicates that the needle guard is locked.
3. After your injection.
Throw the used pre-filled pen away: Put your used pre-filled pen in a sharps disposal container right away after use. Make sure you dispose of the bin as instructed by your doctor or nurse when the container is full.
Check injection site: There may be a small amount of blood or liquid at the injection site. Hold pressure over your skin with a cotton ball or gauze pad until any bleeding stops. Do not rub the injection site. If needed, cover injection site with a bandage. Your injection is now complete.