Ovarian Carcinoma: Primary treatment of advanced ovarian carcinoma (FIGO-stage III, IV) or residual carcinoma (>1 cm) after laparotomy, in combination with cisplatin.
Treatment of metastatic ovarian carcinoma after failure of standard, platinum-containing chemotherapy.
Non-Small Cell Lung Carcinoma: Treatment of non-small cell lung carcinoma (NSCLC) in combination with cisplatin in patients who are not candidates for surgery and/or radiation therapy.
Breast Carcinoma: In combination with trastuzumab for the treatment of metastatic breast carcinoma when tumors overexpress HER2 and patients have not yet received chemotherapy against their metastatic disease.
Treatment of metastatic breast carcinoma in patients who have failed, or are not candidates, for standard anthracycline therapy.
Adjuvant treatment in patients with breast carcinoma and affected local regional lymph nodes (node positive) following anthracycline treatment with doxorubicin and cyclophosphamide.