Synvisc/Synvisc-One

Synvisc/Synvisc-One

Manufacturer:

Sanofi

Distributor:

DCH Auriga - Healthcare
Concise Prescribing Info
Contents
Hylan G-F 20
Indications/Uses
Temporary replacement & supplement for synovial fluid. For patients in all stages of joint pathology. Treatment of pain associated w/ OA of the knee, hip, ankle & shoulder.
Dosage/Direction for Use
IA inj only. Synvisc OA of the knee Three 2 mL inj in the knee, 1 wk apart. Max: 6 inj w/in 6 mth, w/ min 4 wk between treatment regimens. OA of the hip, ankle, shoulder Initially one 2 mL in the knee inj. A 2nd 2 mL inj may be given 1-3 mth after the 1st inj if adequate symptomatic relief is not achieved. Synvisc-One OA of the knee 1 inj in the knee. May be repeated 6 mth after the 1st inj if justified by the patient's symptoms.
Contraindications
Venous or lymphatic stasis in relevant limbs, infected or severely inflamed joints, skin diseases or infections in the area of the inj site.
Special Precautions
Do not inj intravascularly, extra-articularly or into synovial tissues or capsule. Large intra-articular effusion. Avoid strenous activities following IA inj. Hypersensitivity to avian protein. Pregnancy & lactation. Childn <18 yr.
Adverse Reactions
Transient pain/or swelling/or effusion at the injected joint. Synvisc Rarely, rash, hives, itching, fever, nausea, headache, dizziness, chills, muscle cramps, paresthesia, peripheral oedema, malaise, respiratory difficulties, flushing & facial swelling.
Drug Interactions
Do not use concomitantly w/ quaternary ammon salts for skin prep.
MIMS Class
Other Drugs Acting on Musculo-Skeletal System
ATC Classification
M09AX01 - hyaluronic acid ; Belongs to the class of other drugs for disorders of the musculo-skeletal system.
Presentation/Packing
Form
Synvisc syringe 8 mg/mL
Packing/Price
2 mL x 1's
Form
Synvisc-One syringe 8 mg/mL
Packing/Price
6 mL x 1's
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