Caution is recommended w/ concurrent alcohol intake. Caution in patients w/ predisposing factors of urinary retention (eg, spinal cord lesion, prostatic hyperplasia). May increase risk of urinary retention. Caution in patients w/ epilepsy & patients at risk of convulsion. May cause seizure aggravation. Wash-out period (3 days) is required before performing allergy skin tests. Should not be taken by patients w/ rare hereditary problems of galactose intolerance, total-lactase deficiency or glucose-galactose malabsorption. Pruritus may occur upon discontinuation. May impair ability to drive or operate machinery. Pregnancy & lactation. Not recommended in childn <6 yr.
Small decrease in cetirizine clearance w/ theophylline. Increased extent of exposure to cetirizine w/ ritonavir. Decreased rate of absorption w/ food. Co-administration w/ alcohol or other CNS depressants may cause additional reductions in alertness & impairment of performance in sensitive patients.
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