Blepharospasm Initially 1.25-2.5 u (0.05- 0.1 mL at each inj site) injected into the medial & lateral pre-tarsal orbicularis oculi of the upper lid & into the lateral pre-tarsal orbicularis oculi of the lower lid. Treatment can be repeated after approx 3 mth. At repeat treatment sessions, dose may be increased up to 2-fold if there is insufficient response from initial treatment. Max cumulative dose in a 30-day period: 200 u.
Ped cerebral palsy Inj to each of the medial & lateral heads of the gastrocnemius muscles. Max 200 u/patient at a time.
Patient w/ hemiplegia Total dose of 4 u/kg in the affected gastrocnemius muscle.
Patient w/ diplegia 6 u/kg divided between both legs.
Glabellar wrinkles 20 u injected to 2 places on the corrugators muscle for each eye & 1 place on the procerus muscle. Total of 5 sites w/ 0.1 mL/site.
Muscle spasticity: Biceps brachii 100-200 u, up to 4 sites;
flexor digitorum profundus 15-50 u, 1-2 sites;
flexor digitorum sublimis 15-50 u, 1-2 sites;
flexor carpi radialis 15-60 u, 1-2 sites;
flexor carpi ulnaris 10-50 u, 1-2 sites.
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