They are identical with those observed after Levodopa overdosage. If Levodopa dose are not reduced on the basis of the patient's response, both its cerebral effects (hallucination, confusion and hyperkinesia) and its extracerebral effects (first of all gastro-intestinal complaints) may increase. If combined, Levodopa and additional SEFMEX treatment is more favorable, as the risk of extracerebral side effects may decrease.