Adjuvant therapy of severe bacterial infections additional to antibiotic therapy. Ig substitution in immunocompromized patients & patients suffering from severe secondary Ab deficiency syndrome.
IVAdult & childnSevere bacterial infection 5 mL (0.25 g)/kg daily on 3 consecutive days at a rate of 0.4 mL/kg/hr. May be administered alternatively w/ the 1st 100 mL at 0.4 mL/kg/hr then 0.2 mL/kg/hr continuously until 15 mL/kg is reached w/in 72 hr. Ig substitution in immunocompromized patients & in severe secondary Ab deficiency syndrome patients 3-5 mL (0.15-0.25 g)/kg. Repeat at wkly intervals if needed. Neonate & infant 5 mL (0.25 g)/kg daily on 3 consecutive days at a rate of 1.7 mL/kg/hr by infusion pump.
May cause adverse reactions w/ Ca gluconate in infants. Impaired efficacy of live attenuated virus vaccines eg, measles, rubella, mumps & varicella for a period of at least 6 wk & up to 3 mth.
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