Oxair

Oxair

montelukast

Manufacturer:

Y.S.P. Industries

Distributor:

Yung Shin
Concise Prescribing Info
Contents
Montelukast Na
Indications/Uses
Add-on therapy in patients w/ mild to moderate persistent asthma who are inadequately controlled on inhaled corticosteroids & in whom "as-needed" short-acting β-agonists provide inadequate clinical control. Symptomatic relief of seasonal allergic rhinitis in asthmatic patients. Prophylaxis of asthma predominantly due to exercise-induced bronchoconstriction.
Dosage/Direction for Use
Adult & adolescent ≥15 yr One 10-mg tab daily.
Administration
May be taken with or without food.
Special Precautions
Do not use oral montelukast to treat acute asthma attacks. Do not abruptly substitute for inhaled or oral corticosteroids. In rare cases, patients on therapy w/ anti-asthma agents, including montelukast, may present w/ systemic eosinophilia, sometimes presenting w/ clinical features of vasculitis consistent w/ Churg-Strauss syndrome. Treatment does not alter the need for patients w/ aspirin-sensitive asthma to avoid taking aspirin & other NSAIDs. Do not concomitantly use w/ other montelukast-containing products. Patients w/ rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption. Patients w/ severe hepatic impairment. Pregnancy & lactation.
Adverse Reactions
Hypersensitivity reactions (including anaphylaxis, angioedema, rash, pruritus, urticaria & very rarely, hepatic eosinophilic infiltration); dream abnormalities & hallucinations, drowsiness, irritability, restlessness & insomnia; nausea, vomiting, dyspepsia, diarrhea; myalgia including muscle cramps; increased bleeding tendency, bruising; & edema.
Drug Interactions
Decreased AUC w/ phenobarb. Caution w/ CYP3A4, 2C8 & 2C9 inducers eg, phenytoin, phenobarb & rifampicin.
MIMS Class
Antiasthmatic & COPD Preparations
ATC Classification
R03DC03 - montelukast ; Belongs to the class of leukotriene receptor antagonists. Used in the systemic treatment of obstructive airway diseases.
Presentation/Packing
Form
Oxair FC tab 10 mg
Packing/Price
10 × 10's
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