Perform medical exam before & periodically during treatment. Irregular bleeding may occur in case of missed dose for several days in a row. Risk of w/drawal symptoms. Wash hands after application. Allow gel to dry for about 2 min before putting on clothing. Do not apply to breasts or mucous membranes. Perform regular breast exam, especially in patients w/ family history of breast cancer or w/ breast cysts or lumps. Increased risk of developing thromboembolic disease, breast or uterine cancer, & CV incident or cerebral vascular problem. Add progestagen treatment during at least 12 days in the cycle in women w/ intact uterus. Caution in case of allergic reactions; jaundice of eyes & skin; significant increase in arterial tension & BP; unusual leg pain, limb weakness; chest pain, irregular pulse, sudden breathlessness; loss of consciousness, confusion, unusually severe headache, vertigo, visual problem, slowness or loss of speech; breast lumps. Caution in patients w/ HTN, diabetes, endometriosis, uterine fibroma, hepatic or biliary problems, epilepsy, migraine or severe headache, renal or cardiac insufficiency, asthma, lupus, otospongiosis; bed-ridden or surgical patients. Do not take during pregnancy or breast-feeding. Limited experience in women >65 yr.