Individualized dosing. Used in combination w/ intermediate-acting or long-acting insulin given at least once daily. Usual insulin requirement: 0.5-1 u/kg/day. Must be used w/ Novofine or Novotwist disposable needles up to a length of 8 mm.
Inadequate dosing or discontinuation of treatment especially in type 1 diabetes may lead to hyperglycaemia & diabetic ketoacidosis; omission of a meal or unplanned, strenuous physical exercise may lead to hypoglycaemia; concomitant illness, especially infections & feverish conditions; transferring from other insulins; risk of CHF when used in combination w/ thiazolidinediones; insulin antibodies. May impair ability to drive or operate machinery. Pregnancy & lactation.
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