Novofem Dosage/Direction for Use

Novofem is a continuous sequential HRT product for oral use. The oestrogen is dosed continuously. The progestagen is added for 12 days of every 28-day cycle, in a sequential manner.
One tablet is taken daily in the following order: oestrogen therapy (red film-coated tablet) over 16 days, followed by 12 days of oestrogen/progestagen therapy (white film-coated tablet).
After intake of the last white tablet, treatment is continued with the first red tablet of a new pack on the next day. A menstruation-like bleeding usually occurs at the beginning of a new treatment cycle.
In women who are not taking HRT or women in transition from a continuous combined HRT product, treatment with Novofem may be started onany convenient day. In women in transition from another sequential HRT regimen, treatment should begin the day following completion of the preceding regimen.
For initiation and continuation of treatment of postmenopausal symptoms, the lowest effective dose for the shortest duration (see Precautions) should be used.
A switch to a higher dose combination product could be indicated if the response after 3 months is insufficient for symptom relief.
If the patient has forgotten to take a tablet, the tablet should be taken as soon as possible within the next 12 hours. If more than 12 hours have passed, the tablet is to be discarded.
Forgetting a dose may increase the likelihood of breakthrough bleeding and spotting.