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Like all medicines, this medicine can cause side effects, although not everybody gets them.
Very common serious side effects (may affect more than 1 in 10 people): thrombocytopenia; nausea, vomiting and diarrhoea; peripheral neuropathy; peripheral oedema; skin rash that may be itchy and in a few areas or all over the body; bronchitis.
Rare side effects (may affect up to 1 in 1,000 people): Sweet's syndrome or Stevens-Johnson syndrome; transverse myelitis; posterior reversible encephalopathy syndrome; tumour lysis syndrome; thrombotic microangiopathy, thrombotic thrombocytopenic purpura.
Other possible side effects: The following side effects may become severe.
Very common side effects (may affect more than 1 in 10 people): constipation; back pain; upper respiratory tract infection; fatigue; neutropenia; decreased appetite; arrhythmia; vision conditions including blurred vision, dry eye and conjunctivitis.
Common side effects (may affect up to 1 in 10 people): herpes zoster; hypotension; heart failure; jaundice; hypokalaemia.
Reporting of side effects: Side effects should be reported. This includes any possible side effects not previously listed. By reporting side effects, patients can help provide more information on the safety of this medicine.
