Psoriasis vulgaris in patients w/ inadequate response to phototherapies or other existing systemic therapies (except biologics) & those w/ skin eruptions over 10% or more of BSA; in patients w/ intractable skin eruptions.
Patients w/ infections or suspected infections; history of TB; depression or w/ such a history; history of suicidal ideation or attempt; active Crohn's disease. Possible onset of malignant tumors. Avoid live vaccines & other biologics. Pregnancy. Avoid breastfeeding during treatment. Childn. Elderly.