Lamecon

Terbinafine.

Lamecon Tablets are white or off-white, or slightly yellowish, round, flat-faced, scored and beveled-edge.
Each tablet contains 281 mg terbinafine hydrochloride, equivalent to 250 mg terbinafine.
Excipients/Inactive Ingredients: They also contain the inactive ingredients colloidal anhydrous silica, corn starch, hypromellose, magnesium stearate, microcrystalline cellulose and sodium starch glycolate.

Terbinafine, the active ingredient in Lamecon Tablets, is an antifungal medicine.

Lamecon Tablets are used to treat a number of fungal infections of the skin and nails.

Lamecon Tablets should always be taken exactly as prescribed.
The usual dose for adults, including the elderly, is 250 mg once a day.
For skin infections, tablet intake should be continued for 2 to 6 weeks.
For nail infections, treatment usually lasts for between 6 weeks and 3 months, although some patients with toenail infections may need to be treated for 6 months or longer.
If the kidneys are not working very well, the dose of Lamecon Tablets may be reduced.
The tablets should be swallowed whole with a glass of water.
Forgotten dose: The tablet should be taken as soon as it is remembered. The next tablet should be taken at the usual time, then carried on as normal until all the tablets have been finished. It is important to finish all the tablets unless instructed to stop taking them.

All tablets can be risky if taken too many. Medical attention is necessary if too many Lamecon Tablets are taken at once, or patients should be instructed to go to the hospital casualty department as soon as possible and take the medicine pack with them.

Lamecon Tablets must not be taken in case of: allergy to terbinafine or to any of the other ingredients of Lamecon Tablets (listed in Description); existing or history of any liver problems; breast-feeding.

Patients should exercise caution before taking Lamecon Tablets. Lamecon Tablets might not be the right medicine in patients who: are pregnant or trying to become pregnant; have any problems with the kidneys or liver; have psoriasis; have systemic lupus erythematosus (SLE); have rash due to a high level of a specific type of white blood cells.
Blood tests should be performed before and during treatment with Lamecon Tablets to monitor the liver function.
Driving or using machinery: Some people have reported feeling dizzy or giddy while they are taking Lamecon Tablets. Patients should not drive or operate machinery if they feel like this.
Use in Children: Children should not normally be given Lamecon Tablets.

Lamecon Tablets are suitable for most people, but, like all medicines, they can sometimes cause side effects. Any side effects are usually mild or moderate and don't last for too long.
Some side effects can be serious.
Tablet intake should be stopped in case of any of the following rare symptoms: Yellowing of skin or eyes, unusually dark urine or pale faeces, unexplained persistent nausea, stomach problems, loss of appetite or unusual tiredness or weakness (this may indicate liver problems), increase in liver enzymes; Severe skin reactions including rash, light sensitivity, blistering or wheals; Weakness, unusual bleeding, bruising, abnormal pale skin, unusual tiredness, or weakness or breathlessness on exertion or frequent infections (this may be a sign of blood disorders); Difficulty breathing, dizziness, swelling mainly of the face and throat, flushing, crampy abdominal pain, stiffness, rash, fever or swollen/enlarged lymph nodes (possible signs of severe allergic reactions); Symptoms such as rash, fever, itching, tiredness or appearance of purplish spots under the skin surface (signs of blood vessel inflammation); Severe upper stomach pain which spreads to the back (possible signs of pancreas inflammation); Unexplained muscle weakness or pain, or dark (red-brown) urine (possible signs of muscle breakdown).
The most common side effects are: Headache; Stomach problems such as loss of appetite, ache, indigestion, feeling bloated or sick; Diarrhoea; Itching, rash or swelling; Pains in the muscles and joints.
The following side effects have also been reported.
Up to 1 in 100 people have experienced: Taste loss and taste disturbance. This usually disappears within several weeks after stopping the medicine. However, a very small number of people (less than 1 in 10,000) have reported that the taste disturbance lasts for some time and, as a result, they go off their food and lose weight. There have also been reports of some people experiencing anxiety or symptoms of depression as a result of these taste disturbances.
Up to 1 in 1,000 people have experienced: Feeling unwell, dizzy; Numbness or tingling.
Up to 1 in 10,000 people have experienced: Feeling tired; Decrease in the number of some blood cells (seem to bleed or bruise more easily than normal, or easily catch infections that might be more severe than usual); Psoriasis-like skin eruptions, or worsening of any psoriasis including a rash or eruption of small pus-containing blisters; Vertigo; Hair loss; Onset or worsening of lupus.
The following have also been reported: Signs of blood disorders (weakness, unusual bleeding, bruising or frequent infections); Disorders of sense of smell (which may be permanent), impaired hearing, hissing and/or ringing in the ears, flu-like symptoms, increase in blood of creatine phosphokinase, reduced or blurred vision.
Medical attention is necessary if any of the symptoms become troublesome, or in case of anything else not previously mentioned.
Reporting of side effects: Side effects should be reported. This includes any possible side effects not previously listed.

Some medicines can interfere with treatment. It should be known if any of the following are being taken: Rifampicin; Cimetidine; Antidepressants including tricyclic antidepressants, SSRIs (selective serotonin reuptake inhibitors), or MAOIs (monoamine oxidase inhibitors); Oral contraceptives (as irregular periods and breakthrough bleeding may occur in some female patients); Beta-blockers or antiarrhythmics; Warfarin; Heart problem medicines (eg propafenone, amiodarone); Ciclosporin; Antifungal medicines (eg fluconazole, ketoconazole); Cough medicines (eg dextromethorphan); Caffeine.
All medicines being taken should always be noted. This means medicines patients have bought themselves as well as medicines on prescription.

If intake of Lamecon Tablets is to be stopped, any unused tablets should be taken back to the pharmacist to be destroyed. The tablets should only be kept if instructed to. They should not be thrown away with normal household water or waste. This will help to protect the environment.

Store the tablets in their original pack away from direct light.
Store below 25°C.

Antifungals

D01BA02 - terbinafine ; Belongs to the class of antifungals for systemic use.

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